Impact of Earlier Diagnosis in Cardiac ATTR Amyloidosis Over the Course of 20 Years.
Ioannou A, Patel RK, Razvi Y, Porcari A, Sinagra G, Venneri L, Bandera F, Masi A, Williams GE, O'Beara S, Ganesananthan S, Massa P, Knight D, Martinez-Naharro A, Kotecha T, Chacko L, Brown J, Rauf MU, Manisty C, Moon J, Lachmann H, Wechelakar A, Petrie A, Whelan C, Hawkins PN, Gillmore JD, Fontana M.
Ioannou A, et al.
Circulation. 2022 Nov 29;146(22):1657-1670. doi: 10.1161/CIRCULATIONAHA.122.060852. Epub 2022 Nov 3.
Circulation. 2022.
PMID: 36325894
Free PMC article.
Over time, the median duration of associated symptoms before diagnosis fell from 36 months between 2002 and 2006 to 12 months between 2017 and 2021 (Mann-Whitney P<0.001), and a greater proportion of patients had early-stage disease at diagnosis across the 5-year period …
Over time, the median duration of associated symptoms before diagnosis fell from 36 months between 2002 and 2006 to 12 months between 2017 a …